SEMA7A monoclonal antibody (M01), clone 3D3
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SEMA7A.
Immunogen
SEMA7A (NP_003603, 536 a.a. ~ 633 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
EPHKECPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPED
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (87)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.52 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SEMA7A is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — SEMA7A
Entrez GeneID
8482GeneBank Accession#
NM_003612Protein Accession#
NP_003603Gene Name
SEMA7A
Gene Alias
CD108, CDw108, H-SEMA-K1, H-Sema-L, JMH, MGC126692, MGC126696, SEMAK1, SEMAL
Gene Description
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
Omim ID
607961Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds to cell surfaces through a glycosylphosphatidylinositol (GPI) linkage. The encoded glycoprotein is found on activated lymphocytes and erythrocytes. This protein may be involved in immunomodulatory and neuronal processes. Defects in this gene can result in loss of bone mineral density (BMD). Three transcript variants encoding different isoforms have been found for this gene
Other Designations
John Milton Hagen blood group H-Sema K1|sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group)|sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A|semaphorin 7A|semaphorin K1|semaphorin L
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Interactome
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Pathway
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Disease
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