UROD MaxPab mouse polyclonal antibody (B02)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human UROD protein.
Immunogen
UROD (AAH01778, 1 a.a. ~ 367 a.a) full-length human protein.
Sequence
MEANGLGPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCELTLQPLRRFPLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSSTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQVNLDPCALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of UROD expression in transfected 293T cell line (H00007389-T01) by UROD MaxPab polyclonal antibody.
Lane 1: UROD transfected lysate(40.37 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — UROD
Entrez GeneID
7389GeneBank Accession#
BC001778Protein Accession#
AAH01778Gene Name
UROD
Gene Alias
PCT
Gene Description
uroporphyrinogen decarboxylase
Omim ID
176100Gene Ontology
HyperlinkGene Summary
This gene encodes the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria. [provided by RefSeq
Other Designations
OTTHUMP00000010502|fifth enzyme of heme biosynthetic pathway|fifth enzyme of the heme biosynthetic pathway|uroporphyrinogen III decarboxylase
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Interactome
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Pathway
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Disease
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Publication Reference
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Prognostic Significance of UROD Expression on Cervical Cancer With Radiation Therapy.
Kawanaka T, Emma I, Christine H, Fei-Fei L.
International Journal of Radiation Oncology*Biology*Physics 2013 Oct; 87:S130.
Application:IHC-P, Human, Cervical Cancer.
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Prognostic Significance of UROD Expression on Cervical Cancer With Radiation Therapy.
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