UBE2V1 purified MaxPab mouse polyclonal antibody (B02P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human UBE2V1 protein.
Immunogen
UBE2V1 (NP_071887.1, 1 a.a. ~ 103 a.a) full-length human protein.
Sequence
MKEDLNLENFTAKTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (79); Rat (79)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
UBE2V1 MaxPab polyclonal antibody. Western Blot analysis of UBE2V1 expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of UBE2V1 expression in transfected 293T cell line (H00007335-T03) by UBE2V1 MaxPab polyclonal antibody.
Lane 1: UBE2V1 transfected lysate(11.33 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — UBE2V1
Entrez GeneID
7335GeneBank Accession#
NM_022442.3Protein Accession#
NP_071887.1Gene Name
UBE2V1
Gene Alias
CIR1, CROC-1, CROC1, UBE2V, UEV-1, UEV1, UEV1A
Gene Description
ubiquitin-conjugating enzyme E2 variant 1
Omim ID
602995Gene Ontology
HyperlinkGene Summary
Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq
Other Designations
DNA-binding protein|OTTHUMP00000031795|OTTHUMP00000031796|OTTHUMP00000039980
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