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TLR4 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00007099-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-TLR4 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 70.4
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-TLR4 antibody (H00007099-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00007099-T01
    TLR4 transfected lysate.
    Western Blot
    QC Testing of H00007099-T01
    Lane 1: TLR4 transfected lysate ( 70.4 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 7099
  • Protein Accession#:
  • -
  • Gene Name:
  • TLR4
  • Gene Alias:
  • ARMD10,CD284,TOLL,hToll
  • Gene Description:
  • toll-like receptor 4
  • Gene Summary:
  • The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Also, several transcript variants of this gene have been found, but the protein coding potential of most of them is uncertain. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000022807,homolog of Drosophila toll
  • Related Disease
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