TLR2 monoclonal antibody (M15A), clone 3E3
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More Files
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Western Blot (Cell lysate)
TLR2 monoclonal antibody (M15A), clone 3E3. Western Blot analysis of TLR2 expression in HL-60.
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TLR2.
Immunogen
TLR2 (AAH33756.1, 121 a.a. ~ 220 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (61); Rat (62)
Isotype
IgM Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
TLR2 monoclonal antibody (M15A), clone 3E3. Western Blot analysis of TLR2 expression in HL-60.ELISA
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Gene Info — TLR2
Entrez GeneID
7097GeneBank Accession#
BC033756.1Protein Accession#
AAH33756.1Gene Name
TLR2
Gene Alias
CD282, TIL4
Gene Description
toll-like receptor 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq
Other Designations
toll/interleukin 1 receptor-like 4
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Interactome
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Pathway
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Disease
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