Products

Western Blot

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

LEFTY2

Gene Alias

EBAF, LEFTA, LEFTYA, MGC46222, TGFB4

Gene Description

left-right determination factor 2

Omim ID

Gene Ontology

Gene Summary

This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq

Other Designations

OTTHUMP00000035570|endometrial bleeding associated factor|endometrial bleeding associated factor (left-right determination, factor A; transforming growth factor beta superfamily)|transforming growth factor, beta-4 (endometrial bleeding-associated factor;