LEFTY2 monoclonal antibody (M03), clone 1D10
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant LEFTY2.
Immunogen
LEFTY2 (NP_003231, 77 a.a. ~ 180 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RFSQSFREVAGRFLASEASTHLLVFGMEQRLPPNSELVQAVLRLFQEPVPKAALHRHGRLSPRSAQARVTVEWLRVRDDGSNRTSLIDSRLVSVHESGWKAFDV
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — LEFTY2
Entrez GeneID
7044GeneBank Accession#
NM_003240Protein Accession#
NP_003231Gene Name
LEFTY2
Gene Alias
EBAF, LEFTA, LEFTYA, MGC46222, TGFB4
Gene Description
left-right determination factor 2
Omim ID
601877Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq
Other Designations
OTTHUMP00000035570|endometrial bleeding associated factor|endometrial bleeding associated factor (left-right determination, factor A; transforming growth factor beta superfamily)|transforming growth factor, beta-4 (endometrial bleeding-associated factor;
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Interactome
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Pathway
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Disease
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