LEFTY2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human LEFTY2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human LEFTY2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human LEFTY2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — LEFTY2
Entrez GeneID
7044GeneBank Accession#
LEFTY2Gene Name
LEFTY2
Gene Alias
EBAF, LEFTA, LEFTYA, MGC46222, TGFB4
Gene Description
left-right determination factor 2
Omim ID
601877Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq
Other Designations
OTTHUMP00000035570|endometrial bleeding associated factor|endometrial bleeding associated factor (left-right determination, factor A; transforming growth factor beta superfamily)|transforming growth factor, beta-4 (endometrial bleeding-associated factor;
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