TCF7L2 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human TCF7L2 partial ORF ( NP_110383, 490 a.a. - 596 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
SPNLLGSPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQPQPLSLVTKSLE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.51
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TCF7L2
Entrez GeneID
6934GeneBank Accession#
NM_030756Protein Accession#
NP_110383Gene Name
TCF7L2
Gene Alias
TCF-4, TCF4
Gene Description
transcription factor 7-like 2 (T-cell specific, HMG-box)
Gene Ontology
HyperlinkGene Summary
This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes
Other Designations
OTTHUMP00000020496|transcription factor 7-like 2
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Interactome
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Pathway
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Disease
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