TCF7L2 monoclonal antibody (M05), clone 1A1
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant TCF7L2.
Immunogen
TCF7L2 (NP_110383, 490 a.a. ~ 596 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SPNLLGSPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQPQPLSLVTKSLE
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.51 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
TCF7L2 monoclonal antibody (M05), clone 1A1 Western Blot analysis of TCF7L2 expression in K-562 ( Cat # L009V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TCF7L2 is approximately 0.03ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to TCF7L2 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — TCF7L2
Entrez GeneID
6934GeneBank Accession#
NM_030756Protein Accession#
NP_110383Gene Name
TCF7L2
Gene Alias
TCF-4, TCF4
Gene Description
transcription factor 7-like 2 (T-cell specific, HMG-box)
Gene Ontology
HyperlinkGene Summary
This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes
Other Designations
OTTHUMP00000020496|transcription factor 7-like 2
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Interactomes
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