TAF13 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human TAF13 protein.
Immunogen
TAF13 (NP_005636.1, 1 a.a. ~ 124 a.a) full-length human protein.
Sequence
MADEEEDPTFEEENEEIGGGAEGGQGKRKRLFSKELRCMMYGFGDDQNPYTESVDILEDLVIEFITEMTHKAMSIGRQGRVQVEDIVFLIRKDPRKFARVKDLLTMNEELKRARKAFDEANYGS
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of TAF13 expression in transfected 293T cell line (H00006884-T02) by TAF13 MaxPab polyclonal antibody.
Lane 1: TAF13 transfected lysate(14.30 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — TAF13
Entrez GeneID
6884GeneBank Accession#
NM_005645.3Protein Accession#
NP_005636.1Gene Name
TAF13
Gene Alias
MGC22425, TAF2K, TAFII18
Gene Description
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
Omim ID
600774Gene Ontology
HyperlinkGene Summary
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit associated with a subset of TFIID complexes. This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11. There is a pseudogene located on chromosome 6. [provided by RefSeq
Other Designations
OTTHUMP00000039344|TATA box binding protein (TBP)-associated factor, RNA polymerase II, K, 18kD|TBP-associated factor 13|transcription initiation factor TFIID 18 kD subunit
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