Products

Western Blot

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

TAF11

Gene Alias

MGC:15243, PRO2134, TAF2I, TAFII28

Gene Description

TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa

Omim ID

Gene Ontology

Gene Summary

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. [provided by RefSeq

Other Designations

OTTHUMP00000016241|TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28 kD|TATA box binding protein (TBP)-associated factor, RNA polymerase II, I, 28kD|TBP-associated factor 11|TFIID subunit p30-beta|transcription initiation facto