SURF1 MaxPab mouse polyclonal antibody (B01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of SURF1 expression in transfected 293T cell line (H00006834-T01) by SURF1 MaxPab polyclonal antibody.
Lane1:SURF1 transfected lysate(33 KDa).
Lane2:Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SURF1 protein.
Immunogen
SURF1 (NP_003163.1, 1 a.a. ~ 300 a.a) full-length human protein.
Sequence
MAAVAALQLGLRAAGLGRAPASAAWRSVLRVSPRPGVAWRPSRCGSSAAEASATKAEDDSFLQWVLLLIPVTAFGLGTWQVQRRKWKLNLIAELESRVLAEPVPLPADPMELKNLEYRPVKVRGCFDHSKELYMMPRTMVDPVREAREGGLISSSTQSGAYVVTPFHCTDLGVTILVNRGFVPRKKVNPETRQKGQIEGEVDLIGMVRLTETRQPFVPENNPERNHWHYRDLEAMARITGAEPIFIDANFQSTVPGGPIGGQTRVTLRNEHLQYIVTWYGLSAATSYLWFKKFLRGTPGV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (78); Rat (76)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SURF1 expression in transfected 293T cell line (H00006834-T01) by SURF1 MaxPab polyclonal antibody.
Lane1:SURF1 transfected lysate(33 KDa).
Lane2:Non-transfected lysate.
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Gene Info — SURF1
Entrez GeneID
6834GeneBank Accession#
NM_003172.2Protein Accession#
NP_003163.1Gene Name
SURF1
Gene Alias
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Gene Description
surfeit 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. [provided by RefSeq
Other Designations
OTTHUMP00000022473|surfeit locus protein 1
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Interactome
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Disease
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