SSX2 monoclonal antibody (M01), clone 1A4
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of SSX2 expression in transfected 293T cell line by SSX2 monoclonal antibody (M01), clone 1A4.
Lane 1: SSX2 transfected lysate(25.2 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to SSX2 on formalin-fixed paraffin-embedded human testis. [antibody concentration 1.5 ug/ml]
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SSX2 is approximately 0.03ng/ml as a capture antibody.
Western Blot detection against Immunogen (50.27 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant SSX2.
Immunogen
SSX2 (AAH02818, 1 a.a. ~ 223 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MNGDDAFARRPTVGAQIPEKIQKAFDDIAKYFSKEEWEKMKASEKIFYVYMKRKYEAMTKLGFKATLPPFMCNKRAEDFQGNDLDNDPNRGNQVERPQMTFGRLQGISPKIMPKKPAEEGNDSEEVPEASGPQNDGKELCPPGKPTTSEKIHERSGNREAQEKEERRGTAHRWSSQNTHNIGRFSLSTSMGAVHGTPKTITHNRDPKGGNMPGPTDCVRENSW
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (50.27 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SSX2 expression in transfected 293T cell line by SSX2 monoclonal antibody (M01), clone 1A4.
Lane 1: SSX2 transfected lysate(25.2 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to SSX2 on formalin-fixed paraffin-embedded human testis. [antibody concentration 1.5 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SSX2 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — SSX2
Entrez GeneID
6757GeneBank Accession#
BC002818Protein Accession#
AAH02818Gene Name
SSX2
Gene Alias
HD21, HOM-MEL-40, MGC119055, MGC15364, MGC3884, SSX
Gene Description
synovial sarcoma, X breakpoint 2
Omim ID
300192Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000024290|OTTHUMP00000024291|sarcoma, synovial, X-chromosome-related 2|synovial sarcoma, X breakpoint 2, isoform b|synovial sarcoma, X breakpoint 2B
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Interactome
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Publication Reference
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SSX2-4 expression in early-stage non-small cell lung cancer.
Greve KB, Pohl M, Olsen KE, Nielsen O, Ditzel HJ, Gjerstorff MF.
Tissue Antigens 2014 May; 83(5):344.
Application：IHC-P, Human, A375, HCT116, HeLa, MZ2-Mel cells, Testis, Non-small cell lung cancer.
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Expression and Immunotherapeutic Targeting of the SSX Family of Cancer-Testis Antigens in Prostate Cancer.
Smith HA, Cronk RJ, Lang JM, McNeel DG.
Cancer Research 2011 Nov; 71(21):6785.
Application：IHC-P, WB-Re, Human, Human testis tissues.
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SSX2-4 expression in early-stage non-small cell lung cancer.
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