SOX2 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (60.98 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length recombinant SOX2.
Immunogen
SOX2 (AAH13923, 1 a.a. ~ 317 a.a) full-length recombinant protein with GST tag.
Sequence
MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGHRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGYPQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGSMGSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRLHMSQHYQSGPVPGTAINGTLPLSHM
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (60.98 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — SOX2
Entrez GeneID
6657GeneBank Accession#
BC013923Protein Accession#
AAH13923Gene Name
SOX2
Gene Alias
ANOP3, MCOPS3, MGC2413
Gene Description
SRY (sex determining region Y)-box 2
Gene Ontology
HyperlinkGene Summary
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq
Other Designations
SRY-related HMG-box gene 2|sex-determining region Y-box 2|transcription factor SOX2
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Interactome
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Disease
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Publication Reference
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A combined microRNA-based targeted therapeutic approach to eradicate glioblastoma stem-like cells.
Esposito CL,Nuzzo S,Kumar SA,Rienzo A,Lawrence CL,Pallini R,Shaw L,Alder JE,Ricci-Vitiani L,Catuogno S,de Franciscisa V.
Journal of Controlled Release 2016 Sep; 238:43.
Application：WB, Human, U-87 MG cell.
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A combined microRNA-based targeted therapeutic approach to eradicate glioblastoma stem-like cells.
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