SMARCB1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Cell lysate)
SMARCB1 MaxPab polyclonal antibody. Western Blot analysis of SMARCB1 expression in 293.
Western Blot (Transfected lysate)
Western Blot analysis of SMARCB1 expression in transfected 293T cell line (H00006598-T01) by SMARCB1 MaxPab polyclonal antibody.
Lane 1: SMARCB1 transfected lysate(42.35 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to SMARCB1 on formalin-fixed paraffin-embedded human esophagus. [antibody concentration 3 ug/ml]
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to SMARCB1 on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SMARCB1 protein.
Immunogen
SMARCB1 (NP_003064.2, 1 a.a. ~ 385 a.a) full-length human protein.
Sequence
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYLREQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFDDHDPAVIHENASQPEVLVPIRLDMEIDGQKLRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLTFVPAIASAIRQQIESYPTDSILEDQSDQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQKTYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
SMARCB1 MaxPab polyclonal antibody. Western Blot analysis of SMARCB1 expression in 293.Western Blot (Transfected lysate)
Western Blot analysis of SMARCB1 expression in transfected 293T cell line (H00006598-T01) by SMARCB1 MaxPab polyclonal antibody.
Lane 1: SMARCB1 transfected lysate(42.35 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to SMARCB1 on formalin-fixed paraffin-embedded human esophagus. [antibody concentration 3 ug/ml]Immunofluorescence
Immunofluorescence of purified MaxPab antibody to SMARCB1 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — SMARCB1
Entrez GeneID
6598GeneBank Accession#
NM_003073Protein Accession#
NP_003064.2Gene Name
SMARCB1
Gene Alias
BAF47, INI1, RDT, SNF5, SNF5L1, Sfh1p, Snr1, hSNFS
Gene Description
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Omim ID
601607Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
integrase interactor 1|malignant rhabdoid tumor suppressor|sucrose nonfermenting, yeast, homolog-like 1
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Interactome
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Disease
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Publication Reference
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SMARCB1- and vimentin-positive esophageal carcinoma with undifferentiated components, rhabdoid features, and a good prognosis: a case report.
Nagano H, Izumi T, Kawahara E, Oyama T, Goi T.
Surgical Case Reports 2019 Jan; 5(1):8.
Application：IHC, Human, Human esophageal carcinoma.
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SMARCB1- and vimentin-positive esophageal carcinoma with undifferentiated components, rhabdoid features, and a good prognosis: a case report.
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