SGSH MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human SGSH protein.
Immunogen
SGSH (NP_000190.1, 1 a.a. ~ 502 a.a) full-length human protein.
Sequence
MSCPVPACCALLLVLGLCRARPRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRSLLPALEAEPLWATVFGSQSHHEVTMSYPMRSVQHRHFRLVHNLNFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLRHYYYRARWELYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDPWVCAPDGVLEEKLSPQCQPLHNEL
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
SGSH MaxPab rabbit polyclonal antibody. Western Blot analysis of SGSH expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of SGSH expression in transfected 293T cell line (H00006448-T01) by SGSH MaxPab polyclonal antibody.
Lane 1: SGSH transfected lysate(56.70 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of SGSH transfected lysate using anti-SGSH MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with SGSH MaxPab rabbit polyclonal antibody (D01) (H00006448-D01). -
Gene Info — SGSH
Entrez GeneID
6448GeneBank Accession#
NM_000199.2Protein Accession#
NP_000190.1Gene Name
SGSH
Gene Alias
HSS, MPS3A, SFMD
Gene Description
N-sulfoglucosamine sulfohydrolase
Gene Ontology
HyperlinkGene Summary
This gene encodes one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined. [provided by RefSeq
Other Designations
heparan sulfate sulfatase|sulfamidase|sulfoglucosamine sulfamidase
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Interactome
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Pathway
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