SGCG MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Tissue lysate)
SGCG MaxPab rabbit polyclonal antibody. Western Blot analysis of SGCG expression in human kidney.
Western Blot (Transfected lysate)
Western Blot analysis of SGCG expression in transfected 293T cell line (H00006445-T02) by SGCG MaxPab polyclonal antibody.
Lane 1: SGCG transfected lysate(32.40 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of SGCG transfected lysate using anti-SGCG MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with SGCG purified MaxPab mouse polyclonal antibody (B01P) (H00006445-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human SGCG protein.
Immunogen
SGCG (NP_000222.1, 1 a.a. ~ 291 a.a) full-length human protein.
Sequence
MVREQYTTATEGICIERPENQYVYKIGIYGWRKRCLYLFVLLLLIILVVNLALTIWILKVMWFSPAGMGHLCVTKDGLRLEGESEFLFPLYAKEIHSRVDSSLLLQSTQNVTVNARNSEGEVTGRLKVGPKMVEVQNQQFQINSNDGKPLFTVDEKEVVVGTDKLRVTGPEGALFEHSVETPLVRADPFQDLRLESPTRSLSMDAPRGVHIQAHAGKIEALSQMDILFHSSDGMLVLDAETVCLPKLVQGTWGPSGSSQSLYEICVCPDGKLYLSVAGVSTTCQEHSHICL
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
SGCG MaxPab rabbit polyclonal antibody. Western Blot analysis of SGCG expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of SGCG expression in transfected 293T cell line (H00006445-T02) by SGCG MaxPab polyclonal antibody.
Lane 1: SGCG transfected lysate(32.40 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of SGCG transfected lysate using anti-SGCG MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with SGCG purified MaxPab mouse polyclonal antibody (B01P) (H00006445-B01P). -
Gene Info — SGCG
Entrez GeneID
6445GeneBank Accession#
NM_000231.1Protein Accession#
NP_000222.1Gene Name
SGCG
Gene Alias
A4, DAGA4, DMDA, DMDA1, LGMD2C, MAM, MGC130048, SCARMD2, SCG3, TYPE
Gene Description
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
Gene Ontology
HyperlinkGene Summary
This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq
Other Designations
35kD dystrophin-associated glycoprotein|OTTHUMP00000018112|gamma sarcoglycan|sarcoglycan, gamma (35kD dystrophin-associated glycoprotein)
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Interactome
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Pathway
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Disease
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Publication Reference
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Efficient exon skipping of SGCG mutations mediated by phosphorodiamidate morpholino oligomers.
Wyatt EJ, Demonbreun AR, Kim EY, Puckelwartz MJ, Vo AH, Dellefave-Castillo LM, Gao QQ, Vainzof M, Pavanello RCM, Zatz M, McNally EM.
JCI Insight 2018 May; 3(9):99357.
Application：Wb-Tr, Human, iMyoD-transduced fibroblasts.
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Efficient exon skipping of SGCG mutations mediated by phosphorodiamidate morpholino oligomers.
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