CCL15 monoclonal antibody (M02), clone 4G10
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CCL15.
Immunogen
CCL15 (NP_116741, 25 a.a. ~ 113 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
NDAETELMMSKLPLENPVVLNSFHFAADCCTSYISQSIPCSLMKSYFETSSECSKPGVIFLTKKGRQVCAKPSGPGVQDCMKKLKPYSI
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.42 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CCL15 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — CCL15
Entrez GeneID
6359GeneBank Accession#
NM_032965Protein Accession#
NP_116741Gene Name
CCL15
Gene Alias
HCC-2, HMRP-2B, LKN1, Lkn-1, MIP-1d, MIP-5, NCC-3, NCC3, SCYA15, SCYL3, SY15
Gene Description
chemokine (C-C motif) ligand 15
Omim ID
601393Gene Ontology
HyperlinkGene Summary
This gene, CCL15, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene is chemotactic for T cells and monocytes and induces N-acetyl-beta-D-glucosaminidase release in monocytes. It induces changes in intracellular calcium concentration in monocytes and is thought to act through the CCR1 receptor. Read-through transcripts are expressed that include exons from the downstream cytokine gene CCL14, and are represented as GeneID: 348249. [provided by RefSeq
Other Designations
CC chemokine 3|MIP-1 delta|OTTHUMP00000163955|chemokine CC-2|leukotactin 1|macrophage inflammatory protein 5|small inducible cytokine subfamily A (Cys-Cys), member 15
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Interactome
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Pathway
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Disease
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