CCL2 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of CCL2 expression in transfected 293T cell line (H00006347-T02) by CCL2 MaxPab polyclonal antibody.
Lane 1: CCL2 transfected lysate(11.00 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human CCL2 protein.
Immunogen
CCL2 (NP_002973.1, 1 a.a. ~ 99 a.a) full-length human protein.
Sequence
MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCPKEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CCL2 expression in transfected 293T cell line (H00006347-T02) by CCL2 MaxPab polyclonal antibody.
Lane 1: CCL2 transfected lysate(11.00 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CCL2
Entrez GeneID
6347GeneBank Accession#
NM_002982Protein Accession#
NP_002973.1Gene Name
CCL2
Gene Alias
GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF
Gene Description
chemokine (C-C motif) ligand 2
Gene Ontology
HyperlinkGene Summary
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq
Other Designations
monocyte chemoattractant protein-1|monocyte chemotactic and activating factor|monocyte chemotactic protein 1, homologous to mouse Sig-je|monocyte secretory protein JE|small inducible cytokine A2|small inducible cytokine A2 (monocyte chemotactic protein 1,
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Interactome
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Pathway
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Disease
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