RNF6 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human RNF6 peptide using ARM Technology.
Immunogen
A synthetic peptide of human RNF6 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human RNF6 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — RNF6
Entrez GeneID
6049GeneBank Accession#
RNF6Gene Name
RNF6
Gene Alias
DKFZp686P0776
Gene Description
ring finger protein (C3H2C3 type) 6
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. [provided by RefSeq
Other Designations
OTTHUMP00000018154|OTTHUMP00000018155|OTTHUMP00000018156|RING-H2 protein RNF-6|ring finger protein 6
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Interactome
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