REV3L polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant REV3L.
Immunogen
REV3L (NP_002903, 2953 a.a. ~ 3052 a.a) partial recombinant protein with GST tag.
Sequence
GTISQYFTTLHCPVCDDLTQHGICSKCRSQPQHVAVILNQEIRELERQQEQLVKICKNCTGCFDRHIPCVSLNCPVLFKLSRVNRELSKAPYLRQLLDQF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — REV3L
Entrez GeneID
5980GeneBank Accession#
NM_002912Protein Accession#
NP_002903Gene Name
REV3L
Gene Alias
POLZ, REV3
Gene Description
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
Omim ID
602776Gene Ontology
HyperlinkGene Summary
O
Other Designations
OTTHUMP00000017933|OTTHUMP00000017934|OTTHUMP00000040457|Polymerase, DNA, zeta (Rev-3, yeast, homolog of)|REV3-like, catalytic subunit of DNA polymerase zeta|Rev-3, yeast, homolog-like (polymerase, DNA, zeta)
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Interactome
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Pathway
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Disease
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Publication Reference
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REV3L, the catalytic subunit of DNA polymerase ζ, is involved in the progression and chemoresistance of esophageal squamous cell carcinoma.
Zhu X, Zou S, Zhou J, Zhu H, Zhang S, Shang Z, Ding WQ, Wu J, Chen Y.
Oncology Reports 2016 Mar; 35(3):1664.
Application:IF, Human, ECA-109, TE-1 cells.
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REV3L modulates cisplatin sensitivity of non-small cell lung cancer H1299 cells.
Wang W, Sheng W, Yu C, Cao J, Zhou J, Wu J, Zhang H, Zhang S.
Oncology Reports 2015 Sep; 34(3):1460.
Application:IF, Human, H1299 cells.
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REV3L 3'UTR 460 T>C polymorphism in microRNA target sites contributes to lung cancer susceptibility.
Zhang S, Chen H, Zhao X, Cao J, Tong J, Lu J, Wu W, Shen H, Wei Q, Lu D.
Oncogene 2013 Jan; 32(2):242.
Application:WB-Tr, Human, H1299 cells.
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REV3L, the catalytic subunit of DNA polymerase ζ, is involved in the progression and chemoresistance of esophageal squamous cell carcinoma.
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