RAD51 MaxPab mouse polyclonal antibody (B01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human RAD51 protein.
Immunogen
RAD51 (NP_002866, 1 a.a. ~ 339 a.a) full-length human protein.
Sequence
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
Host
Mouse
Reactivity
Human, Mouse, Rat
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Tissue lysate)
RAD51 MaxPab polyclonal antibody. Western Blot analysis of RAD51 expression in human colon.Western Blot (Cell lysate)
RAD51 MaxPab polyclonal antibody. Western Blot analysis of RAD51 expression in PC-12.Western Blot (Cell lysate)
RAD51 MaxPab polyclonal antibody. Western Blot analysis of RAD51 expression in NIH/3T3.Western Blot (Cell lysate)
RAD51 MaxPab polyclonal antibody. Western Blot analysis of RAD51 expression in Jurkat.Western Blot (Cell lysate)
RAD51 MaxPab polyclonal antibody. Western Blot analysis of RAD51 expression in Raw 264.7.Western Blot (Transfected lysate)
Western Blot analysis of RAD51 expression in transfected 293T cell line (H00005888-T01) by RAD51 MaxPab polyclonal antibody.
Lane 1: RAD51 transfected lysate(37.29 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to RAD51 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml] -
Gene Info — RAD51
Entrez GeneID
5888GeneBank Accession#
NM_002875Protein Accession#
NP_002866Gene Name
RAD51
Gene Alias
BRCC5, HRAD51, HsRad51, HsT16930, RAD51A, RECA
Gene Description
RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
BRCA1/BRCA2-containing complex, subunit 5|DNA repair protein RAD51 homolog 1|RAD51 homolog protein|RAD51, S.cerevisiae, homolog of, A|RecA, E. coli, homolog of|RecA-like protein|recombination protein A
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Interactome
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Pathway
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Disease
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Publication Reference
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Increased error-free DNA repair gene expression through reprogramming in human iPS cells.
Yoshimura Y.
Regenerative Therapy 2019 Jun; 11:101.
Application:WB-Ce, Human, Human dermal fibroblasts.
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Increased error-free DNA repair gene expression through reprogramming in human iPS cells.
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