PVR purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PVR protein.
Immunogen
PVR (NP_006496.2, 1 a.a. ~ 417 a.a) full-length human protein.
Sequence
MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGMSRNAIIFLVLGILVFLILLGIGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVSYSAVSRENSSSQDPQTEGTR
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PVR MaxPab rabbit polyclonal antibody. Western Blot analysis of PVR expression in mouse stomach.Western Blot (Transfected lysate)
Western Blot analysis of PVR expression in transfected 293T cell line (H00005817-T01) by PVR MaxPab polyclonal antibody.
Lane 1: PVR transfected lysate(45.30 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PVR
Entrez GeneID
5817GeneBank Accession#
NM_006505Protein Accession#
NP_006496.2Gene Name
PVR
Gene Alias
CD155, FLJ25946, HVED, NECL5, Necl-5, PVS, TAGE4
Gene Description
poliovirus receptor
Omim ID
173850Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
nectin-like 5
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Interactome
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Pathway
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Disease
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Publication Reference
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Identification of hepatic microvascular adhesion-related genes of human colon cancer cells using random homozygous gene perturbation.
Marquez J, Kohli M, Arteta B, Chang S, Li WB, Goldblatt M, Vidal-Vanaclocha F.
International Journal of Cancer 2013 Nov; 133(9):2113.
Application:Flow Cyt, WB-Tr, Human, HT-29 cells.
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Identification of hepatic microvascular adhesion-related genes of human colon cancer cells using random homozygous gene perturbation.
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