PTPRN2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Western Blot
Lane 1: PTPRN2 transfected lysate ( 108.1 KDa)
Lane 2: Non-transfected lysate.
SDS-PAGE Gel
PTPRN2 transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PTPRN2 full-length
Host
Human
Theoretical MW (kDa)
108.57
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PTPRN2 antibody (H00005799-B01) by Western Blots.
Western Blot
Lane 1: PTPRN2 transfected lysate ( 108.1 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
PTPRN2 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PTPRN2
Entrez GeneID
5799GeneBank Accession#
NM_130843Protein Accession#
NP_570858Gene Name
PTPRN2
Gene Alias
IA-2beta, IAR, ICAAR, PTPRP
Gene Description
protein tyrosine phosphatase, receptor type, N polypeptide 2
Omim ID
601698Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq
Other Designations
IAR/receptor-like protein-tyrosine phosphatase|phogrin|protein tyrosine phosphatase receptor pi|tyrosine phosphatase IA-2 beta
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Interactome
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Pathway
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Disease
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