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PTPRN2 Validated Chimera RNAi

  • Catalog # : H00005799-R01V
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  • Specification
  • Product Description:
  • Homo sapiens protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 3, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_002847
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
  • Western blot analysis of PTPRN2 over-expressed 293 cell line, cotransfected with PTPRN2 Validated Chimera RNAi ( Cat # H00005799-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with PTPRN2 monoclonal antibody (M08), clone 7F8 (Cat # H00005799-M08 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
  • Protocol Download
  • Application Image
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
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  • Gene Information
  • Entrez GeneID:
  • 5799
  • Gene Name:
  • PTPRN2
  • Gene Alias:
  • IA-2beta,IAR,ICAAR,PTPRP
  • Gene Description:
  • protein tyrosine phosphatase, receptor type, N polypeptide 2
  • Gene Summary:
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq
  • Other Designations:
  • IAR/receptor-like protein-tyrosine phosphatase,phogrin,protein tyrosine phosphatase receptor pi,tyrosine phosphatase IA-2 beta
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