PSME2 purified MaxPab rabbit polyclonal antibody (D01P)

Catalog # H00005721-D01P

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Size:100 ug
Price: USD $ 376.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Tissue lysate)
Application

Western Blot (Tissue lysate)

PSME2 MaxPab rabbit polyclonal antibody. Western Blot analysis of PSME2 expression in mouse spleen.

Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

PSME2 MaxPab rabbit polyclonal antibody. Western Blot analysis of PSME2 expression in HepG2.

Western Blot (Transfected lysate)
Application

Western Blot (Transfected lysate)

Western Blot analysis of PSME2 expression in transfected 293T cell line (H00005721-T01) by PSME2 MaxPab polyclonal antibody.

Lane 1: PSME2 transfected lysate(27.40 KDa).
Lane 2: Non-transfected lysate.

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against a full-length human PSME2 protein.MaxPab Polyclonal Antibody,MaxPab Polyclonal Antibodies,MaxPab,DNA Immune,DNA Immunization,Immune Technology

    Immunogen

    PSME2 (AAH04368.1, 1 a.a. ~ 239 a.a) full-length human protein.

    Sequence

    MAKPCGVRLSGEARKQVEVFRQNLFQEAEEFLYRFLPQKIIYLNQLLQEDSLNVADLTSLRAPLDIPIPDPPPKDDEMETDKQEKKEVPKCGFLPGNEKVLSLLALVKPEVWTLKEKCILVITWIQHLIPKIEDGNDFGVAIQEKVLERVNAVKTKVEAFQTTISKYFSERGDAVAKASKETHVMDYRALVHERDEAAYGELRAMVLDLRAFYAELYHIISSNLEKIVNPKGEEKPSMY

    Host

    Rabbit

    Reactivity

    Human, Mouse

    Quality Control Testing

    Antibody reactive against mammalian transfected lysate.

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot (Tissue lysate)

    PSME2 MaxPab rabbit polyclonal antibody. Western Blot analysis of PSME2 expression in mouse spleen.

    Western Blot (Cell lysate)

    PSME2 MaxPab rabbit polyclonal antibody. Western Blot analysis of PSME2 expression in HepG2.

    Western Blot (Transfected lysate)

    Western Blot analysis of PSME2 expression in transfected 293T cell line (H00005721-T01) by PSME2 MaxPab polyclonal antibody.

    Lane 1: PSME2 transfected lysate(27.40 KDa).
    Lane 2: Non-transfected lysate.
  • Gene Info — PSME2

    Entrez GeneID

    5721

    GeneBank Accession#

    BC004368.1

    Protein Accession#

    AAH04368.1

    Gene Name

    PSME2

    Gene Alias

    PA28B, PA28beta, REGbeta

    Gene Description

    proteasome (prosome, macropain) activator subunit 2 (PA28 beta)

    Omim ID

    602161

    Gene Ontology

    Hyperlink

    Gene Summary

    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the beta subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three beta and three alpha subunits combine to form a heterohexameric ring. Six pseudogenes have been identified on chromosomes 4, 5, 8, 10 and 13. [provided by RefSeq

    Other Designations

    11S regulator complex beta subunit|MCP activator, 31-kD subunit|activator of multicatalytic protease subunit 2|cell migration-inducing protein 22|proteasome activator 28-beta|proteasome activator hPA28 subunit beta|proteasome activator subunit 2

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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