PDGFRB MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Tissue lysate)
PDGFRB MaxPab rabbit polyclonal antibody. Western Blot analysis of PDGFRB expression in mouse testis.
Western Blot (Transfected lysate)
Western Blot analysis of PDGFRB expression in transfected 293T cell line (H00005159-T01) by PDGFRB MaxPab polyclonal antibody.
Lane 1: PDGFRB transfected lysate(124 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of PDGFRB transfected lysate using anti-PDGFRB MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with PDGFRB purified MaxPab mouse polyclonal antibody (B01P) (H00005159-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PDGFRB protein.
Immunogen
PDGFRB (AAH32224.1, 1 a.a. ~ 1106 a.a) full-length human protein.
Sequence
MRLPGAMPALALKGELLLLSLLLLLEPQISQGLVVTPPGPELVLNVSSTFVLTCSGSAPVVWERMSQEPPQEMAKAQDGTFSSVLTLTNLTGLDTGEYFCTHNDSRGLETDERKRLYIFVPDPTVGFLPNDAEELFIFLTEITEITIPCRVTDPQLVVTLHEKKGDVALPVPYDHQRGFFGIFEDRSYICKTTIGDREVDSDAYYVYRLQVSSINVSVNAVQTVVRQGENITLMCIVIGNEVVNFEWTYPRKESGRLVEPVTDFLLDMPYHIRSILHIPSAELEDSGTYTCNVTESVNDHQDEKAINITVVESGYVRLLGEVGTLQFAELHRSRTLQVVFEAYPPPTVLWFKDNRTLGDSSAGEIALSTRNVSETRYVSELTLVRVKVAEAGHYTMRAFHEDAEVQLSFQLQINVPVRVLELSESHPDSGEQTVRCRGRGMPQPNIIWSACRDLKRCPRELPPTLLGNSSEEESQLETNVTYWEEEQEFEVVSTLRLQHVDRPLSVRCTLRNAVGQDTQEVIVVPHSLPFKVVVISAILALVVLTIISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQHHSDKRRPPSAELYSNALPVGLPLPSHVSLTGESDGGYMDMSKDESVDYVPMLDMKGDVKYADIESSNYMAPYDNYVPSAPERTCRATLINESPVLSYMDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLLGEGYKKKYQQVDEEFLRSDHPAILRSQARLPGFHGLRSPLDTSSVLYTAVQPNEGDNDYIIPLPDPKPEVADEGPLEGSPSLASSTLNEVNTSSTISCDSPLEPQDEPEPEPQLELQVEPEPELEQLPDSGCPAPRAEAEDSFL
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PDGFRB MaxPab rabbit polyclonal antibody. Western Blot analysis of PDGFRB expression in mouse testis.Western Blot (Transfected lysate)
Western Blot analysis of PDGFRB expression in transfected 293T cell line (H00005159-T01) by PDGFRB MaxPab polyclonal antibody.
Lane 1: PDGFRB transfected lysate(124 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of PDGFRB transfected lysate using anti-PDGFRB MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with PDGFRB purified MaxPab mouse polyclonal antibody (B01P) (H00005159-B01P). -
Gene Info — PDGFRB
Entrez GeneID
5159GeneBank Accession#
BC032224.1Protein Accession#
AAH32224.1Gene Name
PDGFRB
Gene Alias
CD140B, JTK12, PDGF-R-beta, PDGFR, PDGFR1
Gene Description
platelet-derived growth factor receptor, beta polypeptide
Gene Ontology
HyperlinkGene Summary
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq
Other Designations
beta platelet-derived growth factor receptor|platelet-derived growth factor receptor beta|soluble PDGFRb variant 1
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Interactome
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Pathway
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Disease
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