PCSK2 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PCSK2 protein.
Immunogen
PCSK2 (NP_002585.2, 1 a.a. ~ 638 a.a) full-length human protein.
Sequence
MKGGCVSQWKAAAGFLFCVMVFASAERPVFTNHFLVELHKGGEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEWTLMLHGTQSAPYIDQVVRDYQSKLAMSKKEELEEELDEAVERSLKSILNKN
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PCSK2 MaxPab rabbit polyclonal antibody. Western Blot analysis of PCSK2 expression in human liver.Western Blot (Tissue lysate)
PCSK2 MaxPab rabbit polyclonal antibody. Western Blot analysis of PCSK2 expression in mouse liver.Western Blot (Transfected lysate)
Western Blot analysis of PCSK2 expression in transfected 293T cell line (H00005126-T01) by PCSK2 MaxPab polyclonal antibody.
Lane 1: PCSK2 transfected lysate(70.60 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PCSK2
Entrez GeneID
5126GeneBank Accession#
NM_002594.2Protein Accession#
NP_002585.2Gene Name
PCSK2
Gene Alias
NEC2, PC2, SPC2
Gene Description
proprotein convertase subtilisin/kexin type 2
Omim ID
162151Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, proenkephalin, prodynorphin and proluteinizing-hormone-releasing hormone. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq
Other Designations
KEX2-like endoprotease 2|OTTHUMP00000030330|neuroendocrine convertase 2|prohormone convertase 2|subtilisin-like prohormone convertases
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Disease
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