PCK1 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of PCK1 expression in transfected 293T cell line (H00005105-T02) by PCK1 MaxPab polyclonal antibody.
Lane 1: PCK1 transfected lysate(69.20 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PCK1 protein.
Immunogen
PCK1 (NP_002582.2, 1 a.a. ~ 622 a.a) full-length human protein.
Sequence
MPPQLQNGLNLSAKVVQGSLDSLPQAVREFLENNAELCQPDHIHICDGSEEENGRLLGQMEEEGILRRLKKYDNCWLALTDPRDVARIESKTVIVTQEQRDTVPIPKTGLSQLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLSKIGIELTDSPYVVASMRIMTRMGTPVLEALGDGEFVKCLHSVGCPLPLQKPLVNNWPCNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRMASRLAKEEGWLAEHMLVLGITNPEGEKKYLAAAFPSACGKTNLAMMNPSLPGWKVECVGDDIAWMKFDAQGHLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLASGVTITSWKNKEWSSEDGEPCAHPNSRFCTPASQCPIIDAAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKIIMHDPFAMRPFFGYNFGKYLAHWLSMAQHPAAKLPKIFHVNWFRKDKEGKFLWPGFGENSRVLEWMFNRIDGKASTKLTPIGYIPKEDALNLKGLGHINMMELFSISKEFWEKEVEDIEKYLEDQVNADLPCEIEREILALKQRISQM
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PCK1 expression in transfected 293T cell line (H00005105-T02) by PCK1 MaxPab polyclonal antibody.
Lane 1: PCK1 transfected lysate(69.20 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PCK1
Entrez GeneID
5105GeneBank Accession#
NM_002591Protein Accession#
NP_002582.2Gene Name
PCK1
Gene Alias
MGC22652, PEPCK-C, PEPCK1, PEPCKC
Gene Description
phosphoenolpyruvate carboxykinase 1 (soluble)
Omim ID
261680Gene Ontology
HyperlinkGene Summary
This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. [provided by RefSeq
Other Designations
OTTHUMP00000031374|PEP carboxykinase|cytosolic phosphoenolpyruvate carboxykinase 1|phosphoenolpyruvate carboxylase|phosphopyruvate carboxylase
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Interactome
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Pathway
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Disease
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