PAX3 monoclonal antibody (M06), clone 3A8
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More Files
- More Functions
Western Blot detection against Immunogen (37.88 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant PAX3.
Immunogen
PAX3 (NP_852122, 307 a.a. ~ 414 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (98)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.88 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — PAX3
Entrez GeneID
5077GeneBank Accession#
NM_181457Protein Accession#
NP_852122Gene Name
PAX3
Gene Alias
CDHS, HUP2, MGC120381, MGC120382, MGC120383, MGC120384, MGC134778, WS1
Gene Description
paired box 3
Gene Ontology
HyperlinkGene Summary
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. [provided by RefSeq
Other Designations
paired box homeotic gene 3|paired domain gene 3|paired domain gene HuP2
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Interactome
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Disease
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