ORC4L purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human ORC4L protein.
Immunogen
ORC4L (NP_002543.2, 1 a.a. ~ 436 a.a) full-length human protein.
Sequence
MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGESNSVLIIGPRGSGKTMLINHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEFPDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPNCPTDVRQWATSSLSWL
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ORC4L MaxPab polyclonal antibody. Western Blot analysis of ORC4L expression in Jurkat.Western Blot (Transfected lysate)
Western Blot analysis of ORC4L expression in transfected 293T cell line (H00005000-T01) by ORC4L MaxPab polyclonal antibody.
Lane 1: ORC4L transfected lysate(47.96 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to ORC4L on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — ORC4L
Entrez GeneID
5000GeneBank Accession#
NM_002552.2Protein Accession#
NP_002543.2Gene Name
ORC4L
Gene Alias
ORC4, ORC4P
Gene Description
origin recognition complex, subunit 4-like (yeast)
Omim ID
603056Gene Ontology
HyperlinkGene Summary
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown to form a core complex with ORC2L, -3L, and -5L. Three alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq
Other Designations
origin recognition complex subunit 4
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Interactome
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Disease
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