OGG1 (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of OGG1 transfected lysate using rabbit polyclonal anti-OGG1 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-OGG1.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-OGG1 (300 ul)
2. Antibody pair for WB: mouse polyclonal anti-OGG1 (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — OGG1
Entrez GeneID
4968Gene Name
OGG1
Gene Alias
HMMH, HOGG1, MUTM, OGH1
Gene Description
8-oxoguanine DNA glycosylase
Gene Ontology
HyperlinkGene Summary
This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq
Other Designations
8-hydroxyguanine DNA glycosylase|OTTHUMP00000122619
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Interactome
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