NPPB purified MaxPab rabbit polyclonal antibody (D01P)
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human NPPB protein.
Immunogen
NPPB (NP_002512.1, 1 a.a. ~ 134 a.a) full-length human protein.
Sequence
MDPQTAPSRALLLLLFLHLAFLGGRSHPLGSPGSASDLETSGLQEQRNHLQGKLSELQVEQTSLEPLQESPRPTGVWKSREVATEGIRGHRKMVLYTLRAPRSPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of NPPB expression in transfected 293T cell line (H00004879-T01) by NPPB MaxPab polyclonal antibody.
Lane 1: NPPB transfected lysate(14.70 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — NPPB
Entrez GeneID
4879GeneBank Accession#
NM_002521Protein Accession#
NP_002512.1Gene Name
NPPB
Gene Alias
BNP
Gene Description
natriuretic peptide precursor B
Omim ID
600295Gene Ontology
HyperlinkGene Summary
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq
Other Designations
OTTHUMP00000002506|OTTHUMP00000044486|brain type natriuretic peptide|natriuretic protein
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