NPY (Human) Recombinant Protein (P02)
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More Files
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Specification
Product Description
Human NPY full-length ORF ( NP_000896.1, 1 a.a. - 97 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MLGNKRLGLSGLTLALSLLVCLGALAEAYPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRYGKRSSPETLISDLLMRESTENVPRTRLEDPAMW
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.3
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NPY
Entrez GeneID
4852GeneBank Accession#
NM_000905.2Protein Accession#
NP_000896.1Gene Name
NPY
Gene Alias
PYY4
Gene Description
neuropeptide Y
Omim ID
162640Gene Ontology
HyperlinkOther Designations
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Interactome
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Pathway
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Disease
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Publication Reference
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Neprilysin-dependent neuropeptide Y cleavage in the liver promotes fibrosis by blocking NPY-receptor 1.
Cristina Ortiz, Sabine Klein, Winfried H Reul, Fernando Magdaleno, Stefanie Gröschl, Peter Dietrich, Robert Schierwagen, Frank E Uschner, Sandra Torres, Christoph Hieber, Caroline Meier, Nico Kraus, Olaf Tyc, Maximilian Brol, Stefan Zeuzem, Christoph Welsch, Marco Poglitsch, Claus Hellerbrand, Mercedes Alfonso-Prieto, Fabio Mira, Ulrich Auf dem Keller, Anja Tetzner, Andrew Moore, Thomas Walther, Jonel Trebicka.
Cell Reports 2023 Jan; 42(2):112059.
Application:IF, LC-MS, Stimulation, Mouse.
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Neprilysin-dependent neuropeptide Y cleavage in the liver promotes fibrosis by blocking NPY-receptor 1.
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