NBL1 (Human) Recombinant Protein (Q01)

Catalog # H00004681-Q01

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Size:25 ug
Price: USD $ 510.00
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Price: USD $ 335.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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QC Test

  • Specification

    Product Description

    Human NBL1 partial ORF ( NP_005371, 21 a.a. - 130 a.a.) recombinant protein with GST-tag at N-terminal.

    Sequence

    INKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSCQACGKEPSHEG

    Host

    Wheat Germ (in vitro)

    Theoretical MW (kDa)

    37.84

    Preparation Method

    in vitro wheat germ expression system

    Purification

    Glutathione Sepharose 4 Fast Flow

    Quality Control Testing

    12.5% SDS-PAGE Stained with Coomassie Blue.

    Storage Buffer

    50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

    Storage Instruction

    Store at -80°C. Aliquot to avoid repeated freezing and thawing.

    Note

    Best use within three months from the date of receipt of this protein.

  • Applications

    Enzyme-linked Immunoabsorbent Assay

    Western Blot (Recombinant protein)

    Antibody Production

    Protein Array

  • Gene Info — NBL1

    Entrez GeneID

    4681

    GeneBank Accession#

    NM_005380

    Protein Accession#

    NP_005371

    Gene Name

    NBL1

    Gene Alias

    D1S1733E, DAN, DAND1, MGC8972, NB, NO3

    Gene Description

    neuroblastoma, suppression of tumorigenicity 1

    Omim ID

    600613

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq

    Other Designations

    differential screening-selected gene aberrant in neuroblastoma|neuroblastoma candidate region, suppression of tumorigenicity 1|neuroblastoma suppressor of tumorigenicity 1

  • Interactome
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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