This gene encodes a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq
Other Designations:
MYH9 variant protein,OTTHUMP00000028706,cellular myosin heavy chain, type A,myosin, heavy polypeptide 9, non-muscle,non-muscle myosin heavy chain,non-muscle myosin heavy polypeptide 9,nonmuscle myosin heavy chain II-A