Immunoprecipitation of MYB transfected lysate using anti-MYB MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with MYB MaxPab mouse polyclonal antibody (B01) (H00004602-B01).
This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq