MUTYH purified MaxPab rabbit polyclonal antibody (D01P)
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human MUTYH protein.
Immunogen
MUTYH (NP_001041636.1, 1 a.a. ~ 535 a.a) full-length human protein.
Sequence
MTPLVSRLSRLWAIMRKPRAAVGSGHRKQAASQEGRQKHAKNNSQAKPSACDGLARQPEEVVLQASVSSYHLFRDVAEVTAFRGSLLSWYDQEKRDLPWRRRAEDEMDLDRRAYAVWVSEVMLQQTQVATVINYYTGWMQKWPTLQDLASASLEEVNQLWAGLGYYSRGRRLQEGARKVVEELGGHMPRTAETLQQLLPGVGRYTAGAIASIAFGQATGVVDGNVARVLCRVRAIGADPSSTLVSQQLWGLAQQLVDPARPGDFNQAAMELGATVCTPQRPLCSQCPVESLCRARQRVEQEQLLASGSLSGSPDVEECAPNTGQCHLCLPPSEPWDQTLGVVNFPRKASRKPPREESSATCVLEQPGALGAQILLVQRPNSGLLAGLWEFPSVTWEPSEQLQRKALLQELQRWAGPLPATHLRHLGEVVHTFSHIKLTYQVYGLALEGQTPVTTVPPGARWLTQEEFHTAAVSTAMKKVFRVYQGQQPGTCMGSKRSQVSSPCSRKKPRMGQQVLDNFFRSHISTDAHSLNSAAQ
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (77)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of MUTYH expression in transfected 293T cell line (H00004595-T01) by MUTYH MaxPab polyclonal antibody.
Lane 1: MUTYH transfected lysate(59.10 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — MUTYH
Entrez GeneID
4595GeneBank Accession#
BC003178.1Protein Accession#
NP_001041636.1Gene Name
MUTYH
Gene Alias
MGC4416, MYH
Gene Description
mutY homolog (E. coli)
Gene Ontology
HyperlinkGene Summary
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
A/G-specific adenine DNA glycosylase|OTTHUMP00000009096|OTTHUMP00000009098|OTTHUMP00000009101|OTTHUMP00000009102|mutY homolog
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Interactome
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Pathway
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Disease
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