SMAD6 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SMAD6 full-length
Host
Human
Theoretical MW (kDa)
54.67
Interspecies Antigen Sequence
Mouse (92)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SMAD6 antibody (H00004091-B01) by Western Blots.
SDS-PAGE Gel
SMAD6 transfected lysate.
Western Blot
Lane 1: SMAD6 transfected lysate ( 54.67 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SMAD6
Entrez GeneID
4091GeneBank Accession#
NM_005585.3Protein Accession#
NP_005576.3Gene Name
SMAD6
Gene Alias
HsT17432, MADH6, MADH7
Gene Description
SMAD family member 6
Omim ID
602931Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants encoding different isoforms have been found for this gene
Other Designations
MAD (mothers against decapentaplegic, Drosophila) homolog 6|MAD, mothers against decapentaplegic homolog 6|Mothers against decapentaplegic, drosophila, homolog of, 6|SMAD, mothers against DPP homolog 6
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Interactome
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Pathway
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Disease
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