SMAD6 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of SMAD6 expression in transfected 293T cell line (H00004091-T02) by SMAD6 MaxPab polyclonal antibody.
Lane 1: SMAD6 transfected lysate(53.50 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to SMAD6 on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human SMAD6 protein.
Immunogen
SMAD6 (NP_005576.3, 1 a.a. ~ 496 a.a) full-length human protein.
Sequence
MFRSKRSGLVRRLWRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPRDASDPLAGAALEPAGGGRSREARSRLLLLEQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGGQPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERSGLQHAPEPDAADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLNNPR
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SMAD6 expression in transfected 293T cell line (H00004091-T02) by SMAD6 MaxPab polyclonal antibody.
Lane 1: SMAD6 transfected lysate(53.50 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to SMAD6 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — SMAD6
Entrez GeneID
4091GeneBank Accession#
NM_005585.3Protein Accession#
NP_005576.3Gene Name
SMAD6
Gene Alias
HsT17432, MADH6, MADH7
Gene Description
SMAD family member 6
Omim ID
602931Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants encoding different isoforms have been found for this gene
Other Designations
MAD (mothers against decapentaplegic, Drosophila) homolog 6|MAD, mothers against decapentaplegic homolog 6|Mothers against decapentaplegic, drosophila, homolog of, 6|SMAD, mothers against DPP homolog 6
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Interactome
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Pathway
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Disease
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