LTA 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-LTA full-length
Host
Human
Theoretical MW (kDa)
22.3
Interspecies Antigen Sequence
Mouse (75); Rat (73)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-LTA antibody (H00004049-D01P) by Western Blots.
SDS-PAGE Gel
LTA transfected lysate.
Western Blot
Lane 1: LTA transfected lysate ( 22.30 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — LTA
Entrez GeneID
4049GeneBank Accession#
BC034729Protein Accession#
AAH34729.1Gene Name
LTA
Gene Alias
LT, TNFB, TNFSF1
Gene Description
lymphotoxin alpha (TNF superfamily, member 1)
Omim ID
153440Gene Ontology
HyperlinkGene Summary
The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis
Other Designations
OTTHUMP00000029184|OTTHUMP00000037612|OTTHUMP00000037613|OTTHUMP00000165897|lymphotoxin alpha|tumor necrosis factor beta
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