LMNA purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
LMNA MaxPab polyclonal antibody. Western Blot analysis of LMNA expression in human pancreas.
Western Blot (Cell lysate)
LMNA MaxPab polyclonal antibody. Western Blot analysis of LMNA expression in A-431.
Western Blot (Transfected lysate)
Western Blot analysis of LMNA expression in transfected 293T cell line (H00004000-T01) by LMNA MaxPab polyclonal antibody.
Lane 1: LMNA transfected lysate(73.04 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to LMNA on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human LMNA protein.
Immunogen
LMNA (NP_733821.1, 1 a.a. ~ 664 a.a) full-length human protein.
Sequence
METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASASGSGAQVGGPISSGSSASSVTVTRSYRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSPQNCSIM
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
LMNA MaxPab polyclonal antibody. Western Blot analysis of LMNA expression in human pancreas.Western Blot (Cell lysate)
LMNA MaxPab polyclonal antibody. Western Blot analysis of LMNA expression in A-431.Western Blot (Transfected lysate)
Western Blot analysis of LMNA expression in transfected 293T cell line (H00004000-T01) by LMNA MaxPab polyclonal antibody.
Lane 1: LMNA transfected lysate(73.04 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to LMNA on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — LMNA
Entrez GeneID
4000GeneBank Accession#
NM_170707.1Protein Accession#
NP_733821.1Gene Name
LMNA
Gene Alias
CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, PRO1
Gene Description
lamin A/C
Gene Ontology
HyperlinkGene Summary
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq
Other Designations
70 kDa lamin|OTTHUMP00000015843|OTTHUMP00000015848
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Interactome
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Pathway
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Disease
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