Products

Western Blot (Transfected lysate)

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

LCP1

Gene Alias

CP64, DKFZp781A23186, FLJ25423, FLJ26114, FLJ39956, L-PLASTIN, LC64P, LPL, PLS2

Gene Description

lymphocyte cytosolic protein 1 (L-plastin)

Omim ID

Gene Ontology

Gene Summary

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq

Other Designations

L-plastin|L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P)|Lymphocyte cytosolic protein-1 (plasmin)|OTTHUMP00000018362|bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin))|plastin 2