KRT81 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-KRT81 full-length
Host
Human
Theoretical MW (kDa)
22.33
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-KRT81 antibody (H00003887-B01) by Western Blots.
SDS-PAGE Gel
KRT81 transfected lysate.
Western Blot
Lane 1: KRT81 transfected lysate ( 22.33 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — KRT81
Entrez GeneID
3887GeneBank Accession#
BC021241.2Protein Accession#
AAH21241.1Gene Name
KRT81
Gene Alias
HB1, Hb-1, KRTHB1, MLN137, ghHkb1, hHAKB2-1
Gene Description
keratin 81
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq
Other Designations
hard keratin, type II, 1|keratin, hair, basic, 1
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