Products

Western Blot (Cell lysate)

KCNH1 polyclonal antibody (A01), Lot # 061110JCS1 Western Blot analysis of KCNH1 expression in SJCRH30 ( Cat # L027V1 ).

Western Blot (Recombinant protein)

ELISA

Entrez GeneID

3756

GeneBank Accession#

NM_172362

Protein Accession#

NP_758872

Gene Name

KCNH1

Gene Alias

EAG, EAG1, Kv10.1, MGC142269, h-eag

Gene Description

potassium voltage-gated channel, subfamily H (eag-related), member 1

Omim ID

603305

Gene Ontology

Hyperlink

Gene Summary

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. [provided by RefSeq

Other Designations

OTTHUMP00000034451|OTTHUMP00000034569|ether-a-go-go potassium channel 1|ether-a-go-go, Drosophila, homolog of|potassium channel, voltage-gated, subfamily H, member 1|potassium voltage-gated channel, subfamily H, member 1