IMPDH2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
IMPDH2 transfected lysate.
Western Blot
Lane 1: IMPDH2 transfected lysate ( 55.80 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-IMPDH2 full-length
Host
Human
Theoretical MW (kDa)
55.8
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-IMPDH2 antibody (H00003615-B01P) by Western Blots.
SDS-PAGE Gel
IMPDH2 transfected lysate.
Western Blot
Lane 1: IMPDH2 transfected lysate ( 55.80 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — IMPDH2
Entrez GeneID
3615GeneBank Accession#
NM_000884.2Protein Accession#
NP_000875.2Gene Name
IMPDH2
Gene Alias
IMPD2, IMPDH-II
Gene Description
IMP (inosine monophosphate) dehydrogenase 2
Omim ID
146691Gene Ontology
HyperlinkGene Summary
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq
Other Designations
IMP dehydrogenase 2|IMP oxireductase 2|inosine 5' phosphate dehydrogenase 2|inosine monophosphate dehydrogenase 2|inosine monophosphate dehydrogenase type II|inosine monophosphate oxireductase 2
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Interactome
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Pathway
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Disease
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