IMPDH2 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of IMPDH2 transfected lysate using mouse monoclonal anti-IMPDH2 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-IMPDH2.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of IMPDH2 transfected lysate using mouse monoclonal anti-IMPDH2 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-IMPDH2.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: mouse monoclonal anti-IMPDH2 (300 ug)
2. Antibody pair for WB: rabbit polyclonal anti-IMPDH2 (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — IMPDH2
Entrez GeneID
3615Gene Name
IMPDH2
Gene Alias
IMPD2, IMPDH-II
Gene Description
IMP (inosine monophosphate) dehydrogenase 2
Omim ID
146691Gene Ontology
HyperlinkGene Summary
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq
Other Designations
IMP dehydrogenase 2|IMP oxireductase 2|inosine 5' phosphate dehydrogenase 2|inosine monophosphate dehydrogenase 2|inosine monophosphate dehydrogenase type II|inosine monophosphate oxireductase 2
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Interactome
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Pathway
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Disease
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