IMPDH1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human IMPDH1 protein.
Immunogen
IMPDH1 (NP_899066.1, 1 a.a. ~ 563 a.a) full-length human protein.
Sequence
MEGPLTPPPLQGGGAAAVPEPGARQHPGHETAAQRYSARLLQAGYEPESMADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
IMPDH1 MaxPab polyclonal antibody. Western Blot analysis of IMPDH1 expression in human spleen.Western Blot (Transfected lysate)
Western Blot analysis of IMPDH1 expression in transfected 293T cell line (H00003614-T01) by IMPDH1 MaxPab polyclonal antibody.
Lane1:IMPDH1 transfected lysate(61.93 KDa).
Lane2:Non-transfected lysate.
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Gene Info — IMPDH1
Entrez GeneID
3614GeneBank Accession#
NM_183243.1Protein Accession#
NP_899066.1Gene Name
IMPDH1
Gene Alias
DKFZp781N0678, IMPD, IMPD1, LCA11, RP10, sWSS2608
Gene Description
IMP (inosine monophosphate) dehydrogenase 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
inosine monophosphate dehydrogenase 1
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Interactome
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Pathway
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Disease
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