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IL12RB1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00003594-T02
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-IL12RB1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 42.4
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-IL12RB1 antibody (H00003594-B02) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00003594-T02
    IL12RB1 transfected lysate.
    Western Blot
    QC Testing of H00003594-T02
    Lane 1: IL12RB1 transfected lysate ( 42.4 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 3594
  • Gene Name:
  • IL12RB1
  • Gene Alias:
  • CD212,IL-12R-BETA1,IL12RB,MGC34454
  • Gene Description:
  • interleukin 12 receptor, beta 1
  • Gene Summary:
  • The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • IL-12 receptor beta component,interleukin-12 receptor beta-1 chain
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